Impact of Endocrine Disrupting Chemicals (EDCs) on Reproductive Health of Human

Abstract At present, endocrine disrupting chemicals (EDCs) have gained attention in human pathophysiology, and many studies yet been conducted to explain the mechanism of these chemical compounds on reproductive dysfunctions. In maximum focus towards exposure their disorders different axises though sufficient information are not available systems human. A huge number EDCs resulting interference normal functions hypothalamic-pituitary–gonadal axis. There several types like pesticides, heavy metals, food additives contaminants which responsible create negative impact metabolism alteration homeostasis tissue promoting such as diabetes, obesity, cardiovascular disease, infertility etc. Genomic nongenomic mechanisms proposed clarify complications together with occupational or environmental together, lack depth studies, occurrence confusing factors prohibited establish causal relationship between cum specific so far. The aim manuscript is review scientific literature exists far hazardous effects health focusing up date mode actions major this concerns.